Synthetic 43-amino-acid peptide based on Thymosin Beta-4. Reference compound for studies of actin sequestration, tissue remodeling, and wound repair pathways.

About TB-500

TB-500 is a synthetic peptide based on a sequence of Thymosin Beta-4 (TB-4), a naturally occurring G-actin sequestering peptide found in nearly all human cells. It has been studied extensively in the context of actin cytoskeleton dynamics, cell migration, and tissue remodeling.

Documented research applications

Used in vitro and in animal model studies investigating:

• Actin sequestration and cytoskeletal regulation
• Cardiac and skeletal muscle remodeling pathways
• Cutaneous wound healing and re-epithelialization
• Endothelial cell migration and angiogenesis
• Hair follicle stem cell research

Origin & quality

Synthesized by solid-phase peptide synthesis (SPPS). Lyophilized white powder. Every lot is independently assayed for identity (HPLC-MS) and purity (RP-HPLC) by a third-party analytical laboratory. See COA above for current lot data.

Handling

Store at −20°C upon receipt. Once reconstituted, store at 2–8°C. Light- and moisture-sensitive.

For research use only. Not for human consumption. Sale restricted to qualified research personnel. Not approved by Health Canada or the FDA for therapeutic use.

All products are supplied for laboratory and research use only and are not for human consumption, diagnostic, or therapeutic use.